ATI Pathophysiology Practice Exam

Which of the following may indicate a hypersecretion of thyroid hormones?

1. Fatigue

2. Weight gain

3. Weight loss

4. Cold intolerance

The correct answer is: Weight loss

Hypersecretion of thyroid hormones, a condition known as hyperthyroidism, can lead to a variety of metabolic changes in the body. One of the hallmark signs of hyperthyroidism is weight loss. This occurs because the excess thyroid hormones increase the metabolic rate, leading to the body burning calories more rapidly than normal. Increased energy expenditure can result in a decrease in body weight, despite normal or increased appetite. Although individuals with hyperthyroidism may experience fatigue, this symptom is more commonly associated with the body's strain due to overactivity rather than indicating an overall reduction in mass. Additionally, weight gain and cold intolerance are more commonly linked to hypothyroidism, where there is a deficiency of thyroid hormones leading to a slower metabolism and energy levels. Thus, weight loss serves as a clear indicator of hypersecretion of thyroid hormones, highlighting the elevated metabolic state caused by these hormones.